You can deduct contributions or gifts that you may have made to various organizations during the tax year. Qualifying contributions can be made in cash, property (clothing, furniture, household items, or vehicles), or out-of-pocket expenses (such as mileage) you paid to do volunteer work for a qualifying organization.
Charitable contributions are an itemized deduction. If your itemized deductions do not surpass your standard deduction, the refund will not be impacted.
For more information on qualified contributions, please review Publication 526.